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GETTING STARTED WITH AWIQLI®

Say goodbye to daily basal insulin. And hello to weekly.

Whether you’re switching from daily basal insulin or starting on basal insulin, your doctor is the first step. We can help you to see what Awiqli® may cost, and how to start the conversation with your doctor.

Actor portrayal
Heathcare provider holding an Awiqli® FlexTouch® pen and talking to patient
Actor portrayals | Image is for illustrative purposes only.

GETTING STARTED WITH AWIQLI®

Say goodbye to daily basal insulin.

And hello to weekly.

Whether you’re switching from daily basal insulin or starting on basal insulin, your doctor is the first step. We can help you to see what Awiqli® may cost, and how to start the conversation with your doctor.

Awiqli® Savings Offer

If you have private or commercial insurance, such as insurance you receive through an employer or purchase yourself, you can pay as little as $35 or no more than $55 per 1-month prescription with the Awiqli® Savings Offer.

Eligible patients pay as little as $35
or no more than $55 per prescription

CHECK YOUR COVERAGE

So, what does your coverage look like?

Your costs depend on your coverage, so here are your options, whether you have private insurance, Medicare, or none at all.

IF YOU HAVE PRIVATE/ COMMERCIAL INSURANCE

Awiqli® Savings Offer

A copay card that may lower what you pay per prescription. Eligibility and other restrictions apply.

IF YOU HAVE MEDICARE PART D

Your insulin cost is capped

You can pay $35 or less for your monthly Awiqli® prescription if you have Medicare Part D insurance that covers Awiqli®.

IF YOU DON'T HAVE INSURANCE

MyInsulinRx™

With this savings program, you may be eligible to pay $55 for a 1-month supply of Awiqli. Offer is available each month during a calendar year. This cost does not apply to any insurance deductible you may have. Eligibility and other restrictions apply.

IF YOU STILL NEED HELP WITH COSTS

NovoCare®

Affordability programs for every insurance type—and help finding the one for you.

TALK TO YOUR DOCTOR

Ask your doctor about Awiqli®

One conversation with your doctor could mean fewer with yourself.

 

You know the ones: Did I take it, When's my next basal insulin dose, Don't forget tonight. A weekly routine with Awiqli® may help you with the day-to-day routines you may have with basal insulin.

 

Here are some ideas how to start it.

Heathcare provider holding an Awiqli® FlexTouch® pen and talking to patient
Actor portrayals | Image is for illustrative purposes only.

Ready to ask about switching? Here's what you should consider.

  • Why you want to switch—such as fewer basal insulin injections or a weekly basal insulin routine
  • The daily basal insulin and other diabetes medicines you take now
  • Any questions about moving from a daily basal insulin to once a week—such as how your dose would change
Image is for illustrative purposes only.

New to insulin?

Here's where to start.

  • Why you're considering insulin now, and what you're hoping it will help with
  • The diabetes medicines you take now
  • What starting insulin would look like—your routine, the injection, and what to expect

FAQs

Questions people often ask about starting Awiqli®.

Awiqli® is available by prescription. Once your doctor prescribes it, your pharmacy can tell you about availability and timing.

Your cost depends on your insurance coverage and any savings programs you qualify for. Your plan and your pharmacist can give you the most accurate number.

NovoCare® offers savings and support resources for eligible patients. Your doctor's office or pharmacist can also point you toward assistance.

Coverage depends on your insurance plan. Novocare® may help you check your coverage and understand your options. You can also ask your healthcare provider, pharmacist, or insurance company whether Awiqli® is covered by your plan.

 NEXT STEP

Before you bring it up—here's how it works.

A quick look at how Awiqli® works in your body, so you can talk it through with your doctor with confidence.

Woman holding and looking down at an Awiqli® FlexTouch® pen
Actor portrayal | Image is for illustrative purposes only.

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

Important Safety Information

Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

Important Safety Information

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700

Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to ISI

What is Awiqli® (insulin icodec-abae) injection 700 units/mL?

  • Prescription Awiqli® is a long-acting insulin (U-700) that is used to control high blood sugar in adults with type 2 diabetes mellitus
  • It is not known if Awiqli® is safe and effective in children and adolescents
  • Awiqli® is available in 1 concentration: U-700
Scroll to Indication

Important Safety Information

Do not share your Awiqli® FlexTouch® pen or needles with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Make sure you use the right type and dose of insulin. Always check the label on your insulin pen before each injection to avoid mix-ups with Awiqli® and other insulin products or injectable medicines used to treat diabetes. If you use another injectable medicine to treat your diabetes, pay close attention to how you select your Awiqli® dosage. The dosage of Awiqli® is different from other injectable medicines used to treat diabetes.

Always make sure that you select the correct dosage of your Awiqli® FlexTouch® pen as prescribed by your healthcare provider, to avoid dosing errors and accidental overdose. People who are blind or have vision problems should not use this pen without help from a person trained to use the pen.

Do not dial the maximum single dosage (700 units) of your Awiqli® FlexTouch® pen, unless prescribed by your healthcare provider.

Do not use a syringe to withdraw Awiqli® from your pen.

Talk to your healthcare provider if you have any questions about how to correctly dose Awiqli® FlexTouch®.

Who should not take Awiqli®?

Do not take Awiqli® if you:

  • are having an episode of low blood sugar (hypoglycemia)
  • have an allergy to Awiqli® or any of the ingredients in Awiqli®. See the full Patient Information for a complete listing of ingredients in Awiqli®

Before taking Awiqli®, tell your healthcare provider about all your medical conditions, including if you are:

  • have liver or kidney problems
  • take other medicines, especially ones called TZDs (thiazolidinediones)
  • have heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Awiqli®
  • pregnant, planning to become pregnant, or are breastfeeding
  • taking new prescription or over-the-counter medicines, vitamins, or herbal supplements

Talk to your health care provider about low blood sugar and how to manage it.

How should I take Awiqli® FlexTouch®?

  • Read the Instructions for Use that come with your Awiqli® FlexTouch® pen
  • Your healthcare provider should show you how to use Awiqli® FlexTouch® pen before you use it for the first time
  • Take Awiqli® exactly as your healthcare provider tells you to. Do not do any conversion of your dose. The dose counter always shows the selected dose in units. Awiqli® FlexTouch® pens are made to deliver your insulin dose in units
  • Know the type and strength of insulin you take. Do not change the type of insulin you take unless your health care provider tells you to. The amount of insulin and best time for you to take your insulin may need to change if you take different types of insulin
  • Inject Awiqli® FlexTouch® 1 time each week on any day of the week on the same day each week
  • If you need to change the day of the week, you may do so if your last dose has been at least 4 days
  • If you have missed your dose, take your missed dose as soon as possible as long as it has been 4 days or less. Then continue the 1 time each week schedule 1 week from the day your missed dose was taken
  • If more than 4 days has passed, skip the missed dose and take your next Awiqli® dose on your regularly scheduled day.
  • Check your blood sugar levels. Ask your health care provider what your blood sugar levels should be and when you should check them
  • Never inject Awiqli® FlexTouch® into a vein or muscle or use Awiqli® in an infusion pump
  • Never use a syringe to remove Awiqli® from the FlexTouch® pen
  • Do not dilute or mix Awiqli® with any other insulin or solution
  • Awiqli® FlexTouch® can be injected under the skin (subcutaneously) of your upper legs (thighs), upper arms, or stomach area (abdomen)
  • Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites.
    • Do not use the exact same spot for each injection
    • Do not inject where the skin has pits, is thickened, or has lumps
    • Do not inject where the skin is tender, bruised, scaly or hard, or into scars or damaged skin
  • Keep Awiqli® and all medicines out of the reach of children.

What should I avoid while taking Awiqli®?

  • Do not drive or operate heavy machinery, until you know how Awiqli® affects you
  • Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol

What are the possible side effects of Awiqli®?

Awiqli® may cause serious side effects that can be life-threatening, including:

  • Low blood sugar (hypoglycemia). Signs and symptoms that may indicate low blood sugar include: dizziness or light-headedness, sweating, confusion, fast heartbeat, blurred vision, slurred speech, shakiness, anxiety, irritability, mood changes, hunger and headache
  • Severe allergic reactions (whole body reaction). Stop using Awiqli® and get medical help right away, if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat or sweating
  • Low potassium in your blood (hypokalemia)
  • Heart failure in some people if taken with thiazolidinediones (TZDs). This can happen even if you have never had heart failure or heart problems. If you already have heart failure, it may get worse while you take TZDs with Awiqli®. Tell your health care provider if you have any new or worse symptoms of heart failure including shortness of breath, tiredness, swelling of your ankles or feet, and sudden weight gain

Your insulin dose may need to change because of change in level of physical activity or exercise, increased stress, change in diet, weight gain or loss, or illness

Common side effects may include: hypoglycemia, serious allergic reactions (whole body reactions), reactions at the injection site, skin thickening or pits at the injection site (lipodystrophy), itching, rash, swelling of your hands and feet, and weight gain

Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, swelling of your face, tongue, or throat, sweating, extreme drowsiness, dizziness, or confusion

These are not all the possible side effects of Awiqli®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Prescribing Information for Awiqli®.

Awiqli® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.